Volume 6, Issue 4, July 2018, Page: 82-85
Factors Predicting Treatment Outcome in Hospitalized Patients with Acute Exacerbation of COPD (AECOPD)
Abhay Uppe, Department of Pulmonary Medicine, D. Y. Patil Medical College, Nerul, Navi Mumbai, India
Padmaraj Ankale, Department of Pulmonary Medicine, D. Y. Patil Medical College, Nerul, Navi Mumbai, India
Arti Sharma, Department of Pulmonary Medicine, D. Y. Patil Medical College, Nerul, Navi Mumbai, India
Ria Shah, Department of Pulmonary Medicine, D. Y. Patil Medical College, Nerul, Navi Mumbai, India
Girija Nair, Department of Pulmonary Medicine, D. Y. Patil Medical College, Nerul, Navi Mumbai, India
Received: Jun. 28, 2018;       Accepted: Jul. 19, 2018;       Published: Aug. 14, 2018
DOI: 10.11648/j.ajim.20180604.16      View  620      Downloads  50
Abstract
Objective: The aim of our study was to study the COPD phenotypes, comorbidities and factors predicting treatment outcomes in patients with acute exacerbations of COPD admitted in hospital. Methodology: A retrospective study of fifty patients with acute exacerbation of COPD admitted in a tertiary care hospital during July 2015 to August 2016 was done. Results: It was observed that the mean duration of hospital stay was 8 ± 7 days with 44% of the patient discharged in less than 7 days (short stay) and 56% of patients in more than 7 days (long stay). The factors favouring longer stay in hospital include history of current smoking, hypoxia and CO2 retention while patients on active COPD treatment and cessation of smoking leads to shorter hospital stay. Conclusion: For patients with acute exacerbations of COPD requiring hospitalization, history of current smoking with hypoxia and CO2 retention are associated with longer stay in hospital while patients on active COPD treatment and cessation of smoking leads to shorter hospital stay.
Keywords
COPD, Hospital Mortality, Intensive Care Unit (ICU), Non-Invasive Ventilation (NIV)
To cite this article
Abhay Uppe, Padmaraj Ankale, Arti Sharma, Ria Shah, Girija Nair, Factors Predicting Treatment Outcome in Hospitalized Patients with Acute Exacerbation of COPD (AECOPD), American Journal of Internal Medicine. Vol. 6, No. 4, 2018, pp. 82-85. doi: 10.11648/j.ajim.20180604.16
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Reference
[1]
Batzlaff CM, Karpman C, Afessa B, Benzo RP. Predicting 1-year mortality rate for patients admitted with an acute exacerbation of chronic obstructive pulmonary disease to an intensive care unit: an opportunity for palliative care. Mayo Clin Proc. 2014 May; 89 (5):638-43. doi: 10.1016/j.mayocp.2013.12.004. Epub 2014 Mar 19.
[2]
Ocal S, Ortac Ersoy E, Ozturk O, Hayran M, Topeli A, Coplu L. Long-term outcome of chronic obstructive pulmonary disease patients with acute respiratory failure following intensive care unit discharge in Turkey. Clin Respir J. 2017 Nov; 11 (6):975-982. doi: 10.1111/crj.12450. Epub 2016 Feb 15.
[3]
Alaithan AM, Memon JI, Rehmani RS, Qureshi AA, Salam A Chronic obstructive pulmonary disease: hospital and intensive care unit outcomes in the Kingdom of Saudi Arabia. Int J Chron Obstruct Pulmon Dis. 2012; 7:819-23. doi: 10.2147/COPD.S37611. Epub 2012 Dec 18.
[4]
Gadre SK, Duggal A, Mireles-Cabodevila E, Krishnan S, Wang XF, Zell K, Guzman J. Acute respiratory failure requiring mechanical ventilation in severe chronic obstructive pulmonary disease (COPD). Medicine (Baltimore). 2018 Apr; 97 (17):e0487. doi: 10.1097/MD.0000000000010487.
[5]
Alvisi V, Romanello A, Badet M, Gaillard S, Philit F, Guérin C. Time course of expiratory flow limitation in COPD patients during acute respiratory failure requiring mechanical ventilation. Chest. 2003 May; 123 (5):1625-32.
[6]
Dikensoy O, Ikidag B, Filiz A, Bayram N. Comparison of non-invasive ventilation and standard medical therapy in acute hypercapnic respiratory failure: a randomised controlled study at a tertiary health centre in SE Turkey. Int. J. Clin. Pract. 2002; 56: 85–8.
[7]
Agarwal R, Gupta R, Aggarwal AN, Gupta D. Noninvasive positive pressure ventilation in acute respiratory failure due to COPD vs other causes: effectiveness and predictors of failure in a respiratory ICU in North India. Int J Chron Obstruct Pulmon Dis. 2008; 3 (4):737-43.
[8]
Abdullah N, Borhanuddin B, Shah SA, Hassan T, Jamal R. Global Lung Initiative 2012 spirometry reference values in a large Asian cohort of Malay, Chinese and Indian ancestry. Respirology. 2018 May 22. doi: 10.1111/resp.13330. [Epub ahead of print].
[9]
National Heart, Lung, and Blood Institute. Unpublished Tabulations from the World Health Organization Mortality Database (Accessed March 2011). Available at: http://www.who.int/whosis/ mort/download/en/index.html.
[10]
García-Sanz MT, González-Barcala FJ, Cánive-Gómez JC, García-Couceiro N, Alonso-Acuña S, Carreira JM. Prolonged stay predictors in patients admitted with chronic obstructive pulmonary disease acute exacerbation. Lung India. 2018 Jul-Aug; 35 (4):316-320. doi: 10.4103/lungindia.lungindia_469_17.
[11]
Lemyre B, Davis PG, De Paoli AG, Kirpalani H. Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation. Cochrane Database Syst Rev. 2017 Feb 1; 2:CD003212. doi: 10.1002/14651858.CD003212.pub3. Review.
[12]
Osadnik CR, Tee VS, Carson-Chahhoud KV, Picot J, Wedzicha JA, Smith BJ. Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2017 Jul 13; 7:CD004104. doi: 10.1002/14651858. CD004104.
[13]
Ocal S, Ortac Ersoy E, Ozturk O, Hayran M, Topeli A, Coplu L. Long-term outcome of chronic obstructive pulmonary disease patients with acute respiratory failure following intensive care unit discharge in Turkey. Clin Respir J. 2017 Nov; 11 (6):975-982. doi: 10.1111/crj.12450. Epub 2016 Feb 15.
[14]
Messer B, Griffiths J, Baudouin SV. The prognostic variables predictive of mortality in patients with an exacerbation of COPD admitted to the ICU: an integrative review. QJM. 2012 Feb; 105 (2):115-26. doi: 10.1093/qjmed/hcr210. Epub 2011 Nov 8. Review.
Browse journals by subject